Aleve 220mg 24 Tablets is an over-the-counter pain reliever and fever reducer formulated with naproxen sodium 220 mg. Aleve’s official product information says it is used for the temporary relief of minor aches and pains such as arthritis pain, muscular aches, backache, menstrual cramps, headache, toothache, and the common cold, and it also temporarily reduces fever. Aleve also states that one dose can provide relief for up to 12 hours.